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Both the combined results of the IVW method (OR common-effect-model = 0.43 [95%CI 0.260.72], OR random-effects-model = 0.42 [95%CI 0.240.76]) and the SMR method (OR common-effect-model = 0.97 [95%CI 0.960.99], OR random-effects-model = 0.97 [95%CI 0.951.00]) showed the consistent trend with the separate results(Fig

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